The product of TAF5L belongs to the WD-repeat TAF5 family of proteins. TAF5L encodes TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. 蛋白別名為：TAF5L; PAF65B; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PCAF-associated factor 65 beta; PAF65-beta;基因ID為：27097；蛋白質ID:O75529
應用類型
WB，IHC-p，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human TAF5L. at AA rangle: 260-340
