TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The Toll-interacting protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. 蛋白別名為:TOLLIP; Toll-interacting protein;基因ID為:54472;蛋白質ID:Q9H0E2
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.