UBR5 encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. 蛋白別名為：UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase; HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein;基因ID為：51366；蛋白質ID:O95071
應用類型
WB，IHC-p，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽：the N-terminal region of human UBR5. at AA rangle: 1-80
