The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. WTAP encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, pre-mRNA-splicing regulator WTAP is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. 蛋白別名為:WTAP; KIAA0105; Pre-mRNA-splicing regulator WTAP; Female-lethal(2)D homolog; hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein;基因ID為:9589;蛋白質ID:Q15007
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human WTAP. at AA rangle: 290-370