BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines.Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.蛋白別名為:BRMS1; Breast cancer metastasis-suppressor 1;基因ID為:25855;蛋白質ID:Q9HCU9
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.