The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. BAG family molecular chaperone regulator 1 encoded by BAG1 binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.蛋白別名為：BAG1; HAP; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1;基因ID為：573；蛋白質ID:Q99933
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
