- 中文名稱
GluR-2 (phospho Ser880) 多克隆抗體
- 英文名字
- GluR-2 (phospho Ser880) Polyclonal Antibody
- 供應商
- 艾美捷
- 產品貨號
- ABP54637
- 產品報價
- ¥替代產品

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.蛋白別名為:GRIA2; GLUR2; Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic; AMPA 2; GluA2;基因ID為:2891;蛋白質ID:P42262
- 應用類型
- WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
- 免疫原
- 合成多肽:human GluR-2 around the phosphorylation site of S880.
- 來源宿主
- 兔
- 反應性
- 人,小鼠,大鼠
- 保存建議
- 廠家推薦藍冰運輸.在發貨后能在-20℃保存1年.為最大限度的避免損失,請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.本產品為液體形式,溶解于PBS緩沖液中,含50%甘油,0.5%BSA和0.02%NaN3.
- 其他
- 艾美捷科技與國內外優秀的生物試劑供應商優保持著密切的合作關系,目前已成為眾多國際知名品牌的中國總代理或一級代理,主要包括:AmyJet、AATBioquest、Abbexa、Abnova、Agrisera、Anogen、Atlas Antibodies、Biosensis、Biovision、BioVendor、CaissonLabs、Cell?Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、HycultBiotech、ImmunoReagents、ImmunoStep、Jackson、LifeSensors、LigaTrap、Lumiprobe、Mabtech、Matreya、NorgenBiotek、Origene、ProImmune、ProSpec、ScyTek、SolisBioDyne、SouthernBiotech、StressMarq、SySy、USBiological、TRC等,可以在短時間內為用戶提供專業的前沿資訊、完備的產品及物流服務。

- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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