A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The EGF containing fibulin like extracellular matrix protein 2 encoded by EFEMP2 contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. 蛋白別名為：EFEMP2; FBLN4; EGF-containing fibulin-like extracellular matrix protein 2; Fibulin-4; FIBL-4; Protein UPH1;基因ID為：30008；蛋白質ID:O95967
應用類型
WB，IHC-p，IF，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human Fibulin-4. at AA rangle: 60-140
