Laminin-R 多克隆抗體-Laminin-R Polyclonal Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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中文名稱: Laminin-R 多克隆抗體

英文名字: Laminin-R Polyclonal Antibody

供應商: 艾美捷

產品貨號: ABP55088

產品報價: ￥替代產品

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背景資料: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. RPSA encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of RPSA exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
蛋白別名為：RPSA; LAMBR; LAMR1; 40S ribosomal protein SA; 37 kDa laminin receptor precursor; 37LRP; 37/67 kDa laminin receptor; LRP/LR; 67 kDa laminin receptor; 67LR; Colon carcinoma laminin-binding protein; Laminin receptor 1; LamR; Laminin-binding pr;基因ID為：3921；蛋白質ID:P08865

應用類型: WB，IHC-p，ELISA
補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.

免疫原: 合成多肽：the Internal region of human Laminin-R.

來源宿主: 兔

反應性: 人，小鼠，大鼠

保存建議: 廠家推薦藍冰運輸.在發貨后能在-20℃保存1年.為最大限度的避免損失，請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.
本產品為液體形式,溶解于PBS緩沖液中，含50%甘油，0.5%BSA和0.02%NaN3.

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