The protein encoded by SAR1B （secretion associated Ras related GTPase 1B） is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in SAR1B are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. 蛋白別名為：SAR1B; SARA2; SARB; GTP-binding protein SAR1b; GTP-binding protein B; GTBPB;基因ID為：51128；蛋白質ID:Q9Y6B6
應用類型
WB，IHC-p，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human Sar1B. at AA rangle: 80-160
