BPIFA1(BPI fold containing family A member 1) is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. 蛋白別名為:BPIFA1; LUNX; NASG; PLUNC; SPURT; BPI fold-containing family A member 1; Lung-specific protein X; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; Secretory protein in upper respiratory tracts; Trach;基因ID為:51297;蛋白質ID:Q9NP55
應用類型
IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.