PMP22 (peripheral myelin protein 22)encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of PMP22 are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.蛋白別名為:PMP22; GAS3; Peripheral myelin protein 22; PMP-22; Growth arrest-specific protein 3; GAS-3;基因ID為:5376;蛋白質ID:Q01453
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human GAS3. at AA rangle: 80-160