CSNK1G1 (casein kinase 1 gamma 1)encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in CSNK1G1 may be associated with non-syndromic early-onset epilepsy (NSEOE).蛋白別名為:CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3;基因ID為:53944/1455/1456;蛋白質ID:Q9HCP0/P78368/Q9Y6M4
應用類型
IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:human Casein Kinase Iγ1/2/3 around the phosphorylation site of Y263.