- 中文名稱
PKAα/β/γ cat (phospho Thr198) 多克隆抗體
- 英文名字
- PKAα/β/γ cat (phospho Thr198) Polyclonal Antibody
- 供應商
- 艾美捷
- 產品貨號
- ABP55741
- 產品報價
- ￥替代產品
- 產品說明書
- 點擊查看
- 購買方式
- 中國區現貨中心已經建立，90%產品中國有現貨庫存。銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- PRKACA（protein kinase cAMP-activated catalytic subunit alpha） encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.蛋白別名為：PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; PRKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; PRKACG; cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gamma;基因ID為：5566/5567；蛋白質ID:P17612/P22694/P22612
- 應用類型
- WB，IHC-p，IF，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
- 免疫原
- 合成多肽：human PKAα/β/γ cat around the phosphorylation site of T198.
- 來源宿主
- 兔
- 反應性
- 人，小鼠，大鼠
- 保存建議
- 廠家推薦藍冰運輸.在發貨后能在-20℃保存1年.為最大限度的避免損失，請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.本產品為液體形式,溶解于PBS緩沖液中，含50%甘油，0.5%BSA和0.02%NaN3.
- 其他
- 艾美捷科技與國內外優秀的生物試劑供應商優保持著密切的合作關系，目前已成為眾多國際知名品牌的中國總代理或一級代理，主要包括：AmyJet、AATBioquest、Abbexa、Abnova、Agrisera、Anogen、Atlas Antibodies、Biosensis、Biovision、BioVendor、CaissonLabs、Cell?Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、HycultBiotech、ImmunoReagents、ImmunoStep、Jackson、LifeSensors、LigaTrap、Lumiprobe、Mabtech、Matreya、NorgenBiotek、Origene、ProImmune、ProSpec、ScyTek、SolisBioDyne、SouthernBiotech、StressMarq、SySy、USBiological、TRC等，可以在短時間內為用戶提供專業的前沿資訊、完備的產品及物流服務。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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