The protein encoded by PRKACB(protein kinase cAMP-activated catalytic subunit beta) is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.蛋白別名為:PRKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta;基因ID為:5567;蛋白質ID:P22694
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human PKAβ cat. at AA rangle: 260-340