CDK5RAP2 (CDK5 regulatory subunit associated protein 2)encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by CDK5RAP2 is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. 蛋白別名為:CDK5RAP2; CEP215; KIAA1633; CDK5 regulatory subunit-associated protein 2; CDK5 activator-binding protein C48; Centrosome-associated protein 215;基因ID為:55755;蛋白質ID:Q96SN8
應用類型
IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human CDK5 Activator-binding C48. at AA rangle: 220-300