ARHGAP22(Rho GTPase activating protein 22) encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for ARHGAP22.蛋白別名為:ARHGAP22; RHOGAP2; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22;基因ID為:58504;蛋白質ID:Q7Z5H3
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human ARHGAP22. at AA rangle: 540-620