Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN4A (sodium voltage-gated channel alpha subunit 4)encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in SCN4A have been linked to several myotonia and periodic paralysis disorders.蛋白別名為:SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4;基因ID為:6329;蛋白質ID:P35499
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Na+ CP type IVα. at AA rangle: 400-480