Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in SLC22A5 （solute carrier family 22 member 5）are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of SLC22A5 results in multiple transcript variants.蛋白別名為：SLC22A5; OCTN2; Solute carrier family 22 member 5; High-affinity sodium-dependent carnitine cotransporter; Organic cation/carnitine transporter 2;基因ID為：6584；蛋白質ID:O76082
應用類型
WB，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human OCTN2. at AA rangle: 270-350
