Stat5a (phospho Ser780) 多克隆抗體-Stat5a (phospho Ser780) Polyclonal Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: The protein encoded by STAT5A（signal transducer and activator of transcription 5A） is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of STAT5A is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for STAT5A.
蛋白別名為：STAT5A; STAT5; Signal transducer and activator of transcription 5A;基因ID為：6776；蛋白質ID:P42229

應用類型: WB，IHC-p，IP，ELISA
補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300. IP: 2-5 ug/mg lysate. ELISA: 1:10000. Not yet tested in other applications.

保存建議: 廠家推薦藍冰運輸.在發貨后能在-20℃保存1年.為最大限度的避免損失，請在打開管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復凍融.
本產品為液體形式,溶解于PBS緩沖液中，含50%甘油，0.5%BSA和0.02%NaN3.

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