TCOF1 （treacle ribosome biogenesis factor 1）encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in TCOF1 have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for TCOF1.蛋白別名為：TCOF1; Treacle protein; Treacher Collins syndrome protein;基因ID為：6949；蛋白質ID:Q13428
應用類型
WB，IHC-p，IF，ELISA補充：最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽：the N-terminal region of human Treacle. at AA rangle: 10-90
