The protein encoded by TH(tyrosine hydroxylase) is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH.蛋白別名為:TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH;基因ID為:7054;蛋白質ID:P07101
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human TH around the phosphorylation site of S62.