WEE1 (WEE1 G2 checkpoint kinase)encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.蛋白別名為:WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase;基因ID為:7465;蛋白質ID:P30291
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human Wee1 around the phosphorylation site of S642.