RASSF7, also named as HRAS1 and HRC1, is a member of the RASSF family contain a highly conserved Ras association domain (RalGDS/AF-6 or RA) and function as Ras effectors tumor suppressors. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. RASSF7 is believed to play an essential role in mitosis. RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis. The antibody can recognizes all the 3 isoform of RASS7.蛋白別名為:RASSF7; C11orf13; HRC1; Ras association domain-containing protein 7; HRAS1-related cluster protein 1;基因ID為:8045;蛋白質ID:Q02833
應用類型
IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human RASSF7. at AA rangle: 130-210