FGF23(fibroblast growth factor 23) encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in FGF23 are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). 蛋白別名為:FGF23; HYPF; Fibroblast growth factor 23; FGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor;基因ID為:8074;蛋白質ID:Q9GZV9
應用類型
WB,IF,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human FGF-23. at AA rangle: 120-200