FZD4(frizzled class receptor 4) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.蛋白別名為:FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344;基因ID為:8322;蛋白質ID:Q9ULV1
應用類型
IF,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Frizzled-4. at AA rangle: 100-180