TCF7L1(transcription factor 7 like 1) encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.蛋白別名為:TCF7L1; TCF3; Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3;基因ID為:83439;蛋白質ID:Q9HCS4
應用類型
WB,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human TCF-3. at AA rangle: 290-370