This protein ALDH1A2 belongs to the aldehyde dehydrogenase family of proteins. The product of ALDH1A2(aldehyde dehydrogenase 1 family member A2) is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for ALDH1A2.蛋白別名為:ALDH1A2; RALDH2; Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II);基因ID為:8854;蛋白質ID:O94788
應用類型
WB,IHC-p,ELISA補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300. Immunocytochemistry: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human ALDH1A2. at AA rangle: 390-470