SOD2(superoxide dismutase 2, mitochondrial) is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of SOD2 results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.蛋白別名為:SOD2; Superoxide dismutase [Mn], mitochondrial;基因ID為:6648;蛋白質ID:P04179
應用類型
WB,IHC-p補充:最優的抗體稀釋比例需要基于客戶實驗進行優化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.