MIB1（mindbomb E3 ubiquitin protein ligase 1） encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).蛋白別名為：MIB1 DIP1 KIAA1323 ZZANK2;基因ID為：57534；蛋白質ID:Q86YT6
