The protein encoded by MYOZ2(myozenin 2) belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in MYOZ2 cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.蛋白別名為:MYOZ2 C4orf5;基因ID為:51778;蛋白質ID:Q9NPC6