SYK (Spleen Associated Tyrosine Kinase) is a Protein Coding gene. Diseases associated with SYK include Hantavirus Pulmonary Syndrome and Mycobacterium Abscessus. Among its related pathways are p70S6K Signaling and RET signaling. SYK encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
