中文名稱

鹽酸阿米洛利（5克）

英文名字

Amiloride hydrochloride

供應商

Alomone

產品貨號

ALO-A-140-5

產品報價

￥已停產

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

Amiloride is a well-known antagonist of ENaC, Na+/Ca2+, and Na+/H+ exchangers, nonselective cation channels, and voltage-gated K+ and Ca2+ channels. It has been extensively used as a probe for a wide variety of transport systems. Amiloride is a nonselective ASIC blocker and the channels cloned all belong to the Amiloride-sensitive Na+-channel. The IC50 values for Amiloride block of ASIC in PC12 cells are 0.2-0.7 μM9, values which are ~10–20 times lower than its block of ASICs in central and sensory neurons. Amiloride inhibits TRPP3 channel activity in Xenopus oocytes with an IC50 value of 143 μM.

產品描述

Blocker of ENaC/ASIC/Degenerin Channels

產品形式

Acid-sensing ion channels (ASICs) are expressed in various sensory and central neurons. Six different ASIC subunits have been cloned, which are encoded by four genes (ASIC1–ASIC4). TRPP3, a member of the transient receptor potential (TRP) superfamily of cation channels, is a Ca2+-activated nonselective cation channel permeable to Ca2+, K+, Na+, Rb+, NH4, and Ba2+, inhibited by Mg2+, H+, La3+, and Gd3+12-13. TRPP3 is localized to a subset of taste receptor cells in the tongue, where it may play a crucial role in sour tasting, and to neurons surrounding the central canal of the spinal cord, where it may account for the long-sought proton-dependent regulation of the frequency of action potential.

保存建議

艾美捷為您提供的Alonmone Labs原裝進口的Amiloride hydrochloride (5 g)產品可室溫運輸，建議您在收到產品后將其置于合適的溫度下保存。

其他

Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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