TRPV3（胞外）-ATTO-633抗體（50 ul）-Anti-TRPV3 （extracellular)-ATTO-633代理/參數/廠家-一抗-艾美捷科技有限公司

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中文名稱: TRPV3（胞外）-ATTO-633抗體（50 ul）

英文名字: Anti-TRPV3 （extracellular)-ATTO-633

供應商: Alomone

產品貨號: ALO-ACC-033-FR-50

產品報價: ￥已停產

產品說明書: 點擊查看

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背景資料: TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells. The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the sixth TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular.According to IUPHAR, the TRP family is comprised of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three additional subfamilies are also considered to belong to the TRP family: the TRPA, TRPML, and TRPP).The TRPV subfamily consists of six members, TRPV1-6.Four members of the TRPV family have been described as a thermosensitive ion channels (TRPV1 to TRPV4). Each channel exhibits distinct thermal activation thresholds ranging from noxious cold (<17°C) to noxious heat (>52°C).TRPV3 is highly expressed in skin keratinocytes. It forms a nonselective cation channel that is activated by hot temperatures in the innocuous and noxious range. The channel is also expressed in oral and nasal cavities where it has been postulated to play a role in flavor sensation. TRPV3 is also implicated as a molecular target of some allergens and skin sensitizers.TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells. The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the sixth TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular.According to IUPHAR, the TRP family is comprised of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three additional subfamilies are also considered to belong to the TRP family: the TRPA, TRPML, and TRPP).The TRPV subfamily consists of six members, TRPV1-6.Four members of the TRPV family have been described as a thermosensitive ion channels (TRPV1 to TRPV4). Each channel exhibits distinct thermal activation thresholds ranging from noxious cold (<17°C) to noxious heat (>52°C).TRPV3 is highly expressed in skin keratinocytes. It forms a nonselective cation channel that is activated by hot temperatures in the innocuous and noxious range. The channel is also expressed in oral and nasal cavities where it has been postulated to play a role in flavor sensation. TRPV3 is also implicated as a molecular target of some allergens and skin sensitizers.

應用類型: 經驗證，該抗體可應用于IC、IH、LC等實驗應用，也可用于 FC

免疫原: TRPV3 (胞外)-ATTO-633抗體的免疫原肽段為(C)REEEAIPHPLALTHK。此免疫原序列來源于464-478位氨基酸殘基，該序列來源于人類TRPV3 (Accession編號為Q8NET8)。第二胞外環。

來源宿主: 兔

反應性: 反應性：人、小鼠、大鼠

保存建議: 艾美捷為您提供的TRPV3 (胞外)-ATTO-633抗體(50 ul)為室溫運輸，建議您收到產品后﹣20℃保存。

其他: Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。