- 中文名稱
GABA（A）Beta1受體抗體（50 ul）
- 英文名字
- Anti-GABA（A) Beta1 Receptor
- 供應商
- Alomone
- 產品貨號
- ALO-AGA-010-50
- 產品報價
- ￥已停產
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868。
- 產品新聞
- 背景資料
- γ-Aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the vertebrate central nervous system (CNS) mediates fast synaptic transmission via ionotropic GABA(A) receptors. These receptors are pentameric assemblies of individual subunits arranged around a central, chloride-conducting pore. To date, 16 human GABA(A) receptor subunit genes have been characterized and grouped together according to their amino acid similarity and termed: α(1–6), β(1–3), δ(1–3), γ, ε, θ, and π1. Each subunit has a large extracellular N-terminal domain, four hydrophobic membrane-spanning domains that form the channel region and a small extracellular C-terminus. These subunits can combine in many different ways to form functional receptors, but most synaptic receptors contain two α subunits (α 1–3 isoforms), two β subunits, and a γ subunit arranged in the order γ-β-α-β-α3.nThe β1 subunit gene is located in the β1- α4- α2- γ1 gene cluster on chromosome , and is most highly expressed in the adult rat hippocampus. GABA(A) R genes are postulated to play a role in neuronal maturation, synaptogenesis, and predisposition to neurological disease. Increases in GABA levels and changes in GABA(A) R subunit gene expression, including decreased β1 mRNA levels, have been observed in animal models of epilepsy. Recent genetic studies have implicated GABA(A) β1 Receptor (GABRB1) in bipolar disorder, schizoaffective disorder and major depression. In addition, GABRB1 is associated with the risk of alcohol dependence
- 應用類型
- 經驗證，該抗體可應用于WB等實驗應用，也可用于IC、IFC、IH、IP等實驗。
- 免疫原
- GABA(A) Beta1 受體 抗體的免疫原肽段為(C)DQSANEKNKLEMNK。此免疫原序列來源于345-358 位氨基酸殘基，該序列來源于大鼠(Accession編號為P15431)。 第二胞內環。
- 來源宿主
- 兔
- 反應性
- 反應性：人、 小鼠、 大鼠
- 保存建議
- 艾美捷為您提供的GABA(A) Beta1 受體 抗體(50 ul)為室溫運輸，建議您收到產品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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