- 中文名稱
GABA（A）Epsilon受體（胞外）-ATTO-633抗體（50 ul）
- 英文名字
- Anti-GABA（A) Epsilon Receptor （extracellular)-ATTO-633
- 供應商
- Alomone
- 產品貨號
- ALO-AGA-015-FR-50
- 產品報價
- ￥已停產
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868。
- 產品新聞
- 背景資料
- GABA (γ-aminobutyric acid) is the major inhibitory neurotransmitter in the brain. Its production, release, reuptake, and metabolism all occur in the nervous system.nThe GABA transmitter interacts with two major types of receptors: ionotropic GABAA receptors (GABAAR) and metabotropic receptors (GABABR). GABAARs belong to the ligand-gated ion channel superfamily. GABA inhibits the activity of signal-receiving neurons by interacting with the GABAA receptor on these cells3. Binding of GABA to its GABAA receptor results in conformational changes that open a Cl- channel, producing an increase in membrane conductance that results in inhibition of neural activity.nGABAARs are heteropentamers, in which all five subunits contribute to the pore formation. To date, eight subunit isoforms have been cloned: α, β, γ, δ, ε, π, θ, and ρ1. Six α subunit isoforms have been found to exist in mammals (α1-α6). In most cases, native GABAA receptors consist of 2α, 2β, and 1γ subunits. The α subunit is the most common and is expressed ubiquitously. It determines the affinity of GABAARs for allosteric ligands.nEach subtype has a unique regional expression in the brain, and individual neurons often express multiple subtypes4. For example, the α4 subunit is detected in the hippocampus, cortex, olfactory bulb and in the basal forebrain. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. ATTO 633 has a maximum absorption at 629 nm and a maximum fluorescence at 657 nm. The fluorescence is excited most efficiently in the range 610 to 645 nm. This label is analogous to the well-known dyes Alexa 647, Alexa 633 and Cy5.
- 應用類型
- 經驗證，該抗體可應用于IC、IH、LCI等實驗應用，也可用于 FC等實驗。
- 免疫原
- GABA(A) Epsilon 受體 (胞外)-ATTO-633抗體的免疫原肽段為(C)RLRYNDTFETLILH。此免疫原序列來源于131-144 位氨基酸殘基，該序列來源于大鼠GABA(A) ε 受體 (Accession編號為Q9ES14)。胞外，N端。
- 來源宿主
- 兔
- 反應性
- 反應性：小鼠、 大鼠、也可反應于： 人
- 保存建議
- 艾美捷為您提供的GABA(A) Epsilon 受體 (胞外)-ATTO-633抗體(50 ul)為室溫運輸，建議您收到產品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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