- 中文名稱
甘氨酸轉運蛋白2(GlyT2)(胞外)抗體(50 ul)
- 英文名字
- Anti-Glycine Transporter 2 (GlyT2) (extracellular)
- 供應商
- Alomone
- 產品貨號
- ALO-AGT-012-50
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868。
- 產品新聞

- 背景資料
- Apart from its obvious biochemical functions, glycine is also an important inhibitory neurotransmitter. Following depolarization, glycine is released from synaptic vesicles, binds to glycine receptors (GlyRs) on postsynaptic membranes thereby causing hyperpolarization of postsynaptic neurons due to the massive influx of Cl- ions. Glycine is then taken up from the synaptic cleft via the glycine transporters GlyT1 and GlyT2 .nGlyT1 and GlyT2 belong to the SLC6, Na+/Cl- dependent transporter family, of which members include transporters for GABA, serotonin, dopamine and norepinephrine2. Like all SLC6 members, GlyT1 and GlyT2 have 12 transmembrane domains and intracellular N- and C-terminals. Both can be found in different splice variants3,4. SLC6 transporters undergo post-translational modifications. For instance, GlyT1 and GlyT2 are glycosylated, which is important for their membrane trafficking5. Phosphorylation of these two transporters also takes place in a PKC-dependent manner, which may lead to down regulation of both transporters6. Pharmacologically, GlyT1 and GlyT2 can be differentiated by applying sarcosine which inhibits GlyT1 but not GlyT2.
- 應用類型
- 經驗證,該抗體可應用于IH、WB等實驗。
- 免疫原
- Glycine Transporter 2 (GlyT2) (胞外)抗體的免疫原肽段為CVIGDHPKIQIKNS。此免疫原序列來源于333-346 位氨基酸殘基,該序列來源于大鼠Glycine Transporter 2 (Accession編號為P58295),第二胞外環。
- 來源宿主
- 兔
- 反應性
- 反應性:小鼠、 大鼠
- 保存建議
- 艾美捷為您提供的Glycine Transporter 2 (GlyT2) (胞外)抗體(50 ul)為室溫運輸,建議您收到產品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證,以凍干粉形式提供,可確保產品生物活性和保質期。Alomone可提供多種包裝規格,靈活方便。作為Alomone Labs在中國的區域總代理,艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

- 注意
-
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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