- 中文名稱
煙堿型乙酰膽堿受體Alpha 4(胞外抗體(50 ul)
- 英文名字
- Anti-Nicotinic Acetylcholine Receptor Alpha 4 (extracellular
- 供應商
- Alomone
- 產品貨號
- ALO-ANC-004-50
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868。
- 產品新聞

- 背景資料
- Acetylcholine, released by cholinergic neurons, activates two groups of acetylcholine receptors (AChRs); muscarinic AChRs (mAChRs) which belong to the superfamily of G-protein coupled receptors (GPCRs) and nicotinic AChRs (nAChRs) which belong to the ligand-gated ion channel superfamily. nAChRs also respond to nicotine, hence their name.nTo date, 17 different but related subunits of nAChRs have been identified and cloned. They consist of α subunits (α1-10), which is responsible for the binding of ligands. In fact, this subunit includes a Cys-loop in the first extracellular domain that is required for agonist binding. The other subunits responsible for making up the active receptor are the β (β1-4), γ, δ and ε subunits. Structurally, all subunits have the following: a conserved large extracellular N-terminal domain, 3 conserved transmembrane domains, a variable cytoplasmic loop and a fourth transmembrane domain with a short extracellular C-terminal domain. An active nAChR is generally a heteropentamer (homopentamers also exist) of these various subunits organized around a central pore
- 應用類型
- 經驗證,該抗體可應用于IFC、IH、WB等實驗應用,也可用于 IC、IP、LCI等實驗。
- 免疫原
- Nicotinic Acetylcholine 受體 Alpha 4 (extracellular抗體的免疫原肽段為(C)DLVNMHSRVDQLD。此免疫原序列來源于190-202位氨基酸殘基,該序列來源于人類nAChRα4 (Accession編號為P43681)。胞外,N端。
- 來源宿主
- 兔
- 反應性
- 反應性:人、 小鼠、 大鼠
- 保存建議
- 艾美捷為您提供的Nicotinic Acetylcholine 受體 Alpha 4 (extracellular抗體(50 ul)為室溫運輸,建議您收到產品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證,以凍干粉形式提供,可確保產品生物活性和保質期。Alomone可提供多種包裝規格,靈活方便。作為Alomone Labs在中國的區域總代理,艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

- 注意
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該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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