Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes nerve growth factor (NGF) neurotrophin-3 (NT-3) and neurotrophin-4/5 (NT-4/5).nAll neurotrophins are synthesized as preproneurotrophin precursors that are subsequently processed within the intracellular transport pathway to yield proneurotrophins that are further processed to generate the mature form. The mature form of BDNF is a non-covalent stable homodimer that can be secreted in both constitutive and regulated pathways.
應用類型
經驗證，該抗體可應用于FC、IH等實驗應用，也可用于 IC 等實驗。
免疫原
proBDNF-ATTO-488 抗體的免疫原肽段為(C)DEDQKVRPNEENNKDAD。此免疫原序列來源于72-88位氨基酸殘基，該序列來源于人類BDNF (precursor) (Accession編號為P23560 )。 Pro結構域 of the BDNF蛋白。
