Kir2.1 is a member of the family of inward rectifying K+ channels. The family includes 15 members that are structurally and functionally different from the voltage-dependent K+ channels.The family’s topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functional unit for the Kir channels is composed of four subunit that can assembly as either homo or heterotetramers.
應用類型
經驗證，該抗體可應用于IC、IFC、IH、IP、WB等實驗。
免疫原
Kir2.1抗體的免疫原肽段為(C)NGVPESTSTDTPPDIDLHN。此免疫原序列來源于392-410位氨基酸殘基，該序列來源于人類Kir2。1 (Accession編號為P48049)。胞內, C-terminal part
