- 中文名稱
HCN3抗體(50 ul)
- 英文名字
- Anti-HCN3
- 供應商
- Alomone
- 產品貨號
- ALO-APC-057-50
- 產品報價
- ¥已停產

- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金,在線支付寶及網銀支付,或直接與我們電話聯系400-6800-868。
- 產品新聞

- 背景資料
- Hyperpolarization-activated cation currents (Ih) appear in the heart and the brain and play a crucial role in controlling electrical pacemaker activity, contributing to biological processes such as heartbeat, sleep-wake cycle and synaptic plasticity.nThe Ih currents are generated by the Hyperpolarization-activated Cyclic Nucleotide-gated channel family (HCN), which comprises of four homologous members, named HCN1-4. Each HCN subunit consist of six transmembrane domains (TM), a pore region between TM5-TM6 and a binding domain to cyclic nucleotides (CNBD) in the cytoplasmic C-terminus.nThe HCN subunits can form functional homomers and can also co-assemble into functionally heteromers.nThe channels are closely related to each other and share homology of about 60%. However, they differ from each other in their cytoplasmic N- and the C-terminus. HCN1-4 mainly differ from each other with regard to their speed of activation and the extent by which they are modulated by cAMP. HCN1 is the fastest channel, followed by HCN2, HCN3 and HCN4.nThe HCN3 channels are abundant in the brain where high expression of HCN3 mRNA was found in the hypothalamus.
- 應用類型
- 經驗證,該抗體可應用于IH、WB等實驗應用,也可用于IC、IFC、IP等實驗。
- 免疫原
- HCN3抗體的免疫原肽段為(C)QRATGDGSPRRKGSGSER 對應的氨基酸殘基: 727-744 位氨基酸殘基,該序列來源于大鼠HCN3 (Accession編號為Q9JKA8)。胞內, C端。
- 來源宿主
- 兔
- 反應性
- 反應性:人、 小鼠、 大鼠
- 保存建議
- 艾美捷為您提供的HCN3抗體(50 ul)為室溫運輸,建議您收到產品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證,以凍干粉形式提供,可確保產品生物活性和保質期。Alomone可提供多種包裝規格,靈活方便。作為Alomone Labs在中國的區域總代理,艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

- 注意
-
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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