Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues. In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both stimulatory and inhibitory manner.Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors. Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.
應用類型
經驗證，該抗體可應用于WB
免疫原
Somatostatin 受體 Type I (胞外)抗體的免疫原肽段為CSRGPGSGAADGMEE。此免疫原序列來源于26-40 位氨基酸殘基，該序列來源于大鼠somatostatin 受體 type 1 (Accession編號為# P28646)。胞外，N端。
來源宿主
兔
反應性
反應性：大鼠
保存建議
艾美捷為您提供的Somatostatin 受體 Type I (胞外)抗體(50 ul)為室溫運輸，建議您收到產品后﹣20℃保存。
