中文名稱

（+）-雙瓜氨酸（250毫克）

英文名字

(+)-Bicuculline

供應商

Alomone

產品貨號

ALO-B-135-250

產品報價

￥已停產

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

GABA is an agonist of two main receptor classes in the CNS: GABAA, an ionic ligand gated channel, and GABAB, a metabotrophic, G-protein coupled receptor. GABAA is assembled by 5 out of 16 possible subunits with α, β and either a γ or a δ (2:2:1 stoichiometry) being the most common. With an EC50 between 3 to 12 μM it interacts with GABA to allow either an influx or an efflux of Cl- ions into and out of the cell, respectively.nBicuculline (BIC) is a competitive allosteric inhibitor of GABAA-induced currents with an IC50 of 1-3 μM. BIC has been employed to model epileptic seizures in hippocampal slices; to induce schizophrenia-like symptoms in the pre-frontal cortex; and is an essential research tool in the study of various psychomotor and behavioral defects.

產品描述

A Potent Antagonist of GABA(A) Receptor Channels

產品形式

γ-aminobutyric acid (GABA) is an amino acid derivate, synthesized from glutamate by the pyridoxal-L-phosphate (PLP)-dependent enzyme, glutamate decarboxylase (GAD). GABA provides the primary inhibitory signaling in the adult mammalian brain (CNS), and, to some degree of controversy, exerts a depolarizing response in the developing brain.

保存建議

艾美捷為您提供的Alonmone Labs原裝進口的(+)-Bicuculline (250 mg)產品可室溫運輸，建議您在收到產品后將其置于合適的溫度下保存。

其他

Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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