Chelerythrine is a potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM) that binds to the catalytic domain of PKC. Chelerythrine is at least 100-fold more selective for PKCs than for other kinases. nIn platelets, Chelerythrine inhibits thromboxane formation and phosphoinositide metabolism. It has an inhibitory effect on ACh-induced current in PC12 cells.
產品描述
A Protein Kinase C Inhibitor
產品形式
Chelerythrine is a potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM) that binds to the catalytic domain of PKC. Chelerythrine is at least 100-fold more selective for PKCs than for other kinases. nIn platelets, Chelerythrine inhibits thromboxane formation and phosphoinositide metabolism. It has an inhibitory effect on ACh-induced current in PC12 cells.
保存建議
艾美捷為您提供的Alonmone Labs原裝進口的Chelerythrine (5 x 1 mg)產品可室溫運輸,建議您在收到產品后將其置于合適的溫度下保存。