鈣西汀（70 ug）-Calciseptine代理/參數/廠家-生化試劑-艾美捷科技有限公司

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背景資料: Calciseptine is a natural peptide isolated from the Dendroaspis p. polylepsis black mamba venom, by a modification to the procedure of Schweitz et al. and purified to homogenity. Calciseptine was shown to be a specific L-type Cav channel blocker. In contrast, it increases L-type currents in skeletal muscle.Calciseptine blocks spontaneous or K+-induced contraction of cardiac and smooth muscle cells. Using patch clamp, it was also shown to block specifically L-type Cav channel current in neuronal cells in culture. For these variety of effects, the IC50's were in the range of 15-500 nM. Using the outside-out configuration of patch clamp, it was shown to reduce single L-type channels open probability and availability as recorded from Guinea pig portal vein.

產品形式: Calciseptine is a natural peptide isolated from the Dendroaspis p. polylepsis black mamba venom, by a modification to the procedure of Schweitz et al. and purified to homogenity. Calciseptine was shown to be a specific L-type Cav channel blocker. In contrast, it increases L-type currents in skeletal muscle.Calciseptine blocks spontaneous or K+-induced contraction of cardiac and smooth muscle cells. Using patch clamp, it was also shown to block specifically L-type Cav channel current in neuronal cells in culture. For these variety of effects, the IC50's were in the range of 15-500 nM. Using the outside-out configuration of patch clamp, it was shown to reduce single L-type channels open probability and availability as recorded from Guinea pig portal vein.

保存建議: 艾美捷為您提供的Alonmone Labs原裝進口的Calciseptine (70 μg)產品可室溫運輸，建議您在收到產品后將其置于合適的溫度下保存。

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