中文名稱

1,1-二甲基-4-苯基哌嗪碘化物（10克）

英文名字

1,1-Dimethyl-4-phenylpiperazinium iodide

供應商

Alomone

產品貨號

ALO-D-125-10

產品報價

￥已停產

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

1,1-Dimethyl-4-phenylpiperazinium iodide (DMPP) is a selective nAChR agonist. For a long time, DMPP was considered to be the prototype of ganglionic stimulating agents, since it was able to activate the nicotinic receptor in sympathetic ganglia with higher potency than the muscle-type. However, it has since been shown that DMPP binds with higher affinity to the nicotinic receptor in the brain. 1,1-Dimethyl-4-phenylpiperazinium iodide activates had IC50 of 0.77 uM on α4 nicotinic channel expressed in xenopus oocytes.

產品描述

An Agonist of nAChR

產品形式

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels comprising five subunits. The muscle-type receptor is made of two α1 β, γ and δ subunits, while the neuronal nicotinic receptors are formed by different combination of 2 α and 3 β subunits. These receptors are expressed on neuronal and different types of non-neuronal cells like: lymphocytes, alveolar macrophages, airway smooth muscle cells, epithelial cells, and fibroblasts.nnAChRs mediate numerous specific physiological functions depending on the type of cell involved. For example, nicotine induces the release of dopamine in the central nervous system and stimulates nitric oxide (NO) synthase gene expression in endothelial cells.

保存建議

艾美捷為您提供的Alonmone Labs原裝進口的1,1-Dimethyl-4-phenylpiperazinium iodide (10 g)產品可室溫運輸，建議您在收到產品后將其置于合適的溫度下保存。

其他

Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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