MT-7 is a 65 amino acid peptide toxin isolated from the Dendroaspis angusticeps (Eastern green mamba). It was first found to inhibit M1 muscarinic receptors stably transfected in CHO cells at very low concentrations (1-30 nM)6 and acts as a non-competitive antagonist by binding to an allosteric site.
產品描述
An Antagonist of M1 Muscarinic Receptor
產品形式
The action of the neurotransmitter acetylcholine (Ach) is mediated through two types of receptors, the ionotropic nicotinic receptors and the metabotropic muscarinic receptors. The muscarinic receptors belong to the superfamily of G-protein coupled receptors. Five subtypes of muscarinic receptors have been cloned: m1-m5.
保存建議
艾美捷為您提供的Alonmone Labs原裝進口的MT-7 (5 X 20 μg)產品可室溫運輸,建議您在收到產品后將其置于合適的溫度下保存。