中文名稱

雷諾嗪（1克）

英文名字

Ranolazine

供應商

Alomone

產品貨號

ALO-R-110-1

產品報價

￥已停產

產品說明書

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購買方式

銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料

Ranolazine is an antianginal and anti-ischemic drug that is used in patients with chronic angina. Ranolazine displays a broad pharmacological profile on a number of targets and has complex electrophysiological effects in myocardium. This drug seems to preferentially reduce the persistent late cardiac NaV1.5 Na+ currents with a 50% inhibitory concentration (IC50) of 15 μM, whereas normal transient Na+ currents are less affected, with an IC50 of 135 μM4. The binding site of ranolazine in human cardiac Na+ channels is probably the same as the local anesthetic (LA) receptor within the inner cavity of the Na+ channel, because a single mutation in this channel (e.g., residue hNav1.5-F1760A) alters the ranolazine binding affinity drastically.

產品描述

A Blocker of Voltage-Gated Na+ Channels

產品形式

Voltage-gated Na+ (NaV) channels are essential for the generation and propagation of action potentials in excitable membranes. The NaV channel protein contains four homologous domains (D1-D4), each with six transmembrane segments (S1-S6). There are 9 isoforms (NaV1.1-1.9) found among mammalian excitable tissues, including central nervous system, peripheral nervous system, skeletal muscle, and heart.

保存建議

艾美捷為您提供的Alonmone Labs原裝進口的Ranolazine (1 g)產品可室溫運輸，建議您在收到產品后將其置于合適的溫度下保存。

其他

Alomone成立于1989年,已經成為全世界科學家信賴的最全面的離子通道研究工具供應商。產品覆蓋離子通道、G蛋白耦聯受體和神經信號研究所需的一抗、小分子、蛋白質和多肽等。所有Alomone產品均進行了生物實驗驗證，以凍干粉形式提供，可確保產品生物活性和保質期。Alomone可提供多種包裝規格，靈活方便。作為Alomone Labs在中國的區域總代理，艾美捷科技有限公司將為中國客戶提供最全面的Alomone Labs產品以及客戶訂制化服務。

注意

該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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