αA-Conotoxin OIVA (αA-OIVA) is a peptidyl toxin originally isolated from Conus obscures and belongs to the family of short αA-conotoxins (αAS) which includes αA-OIVA, αA-OIVB, αA-PeIVA, and αA-PeIVB. αA-Conotoxin OIVA blocks the fetal muscular subtype nicotinic acetylcholine receptor (α1/β1/γ/δ subunits) (IC50 = 0.51 nM) with 600-fold greater affinity than the adult subtype (IC50 = 310 nM). It completely blocks the elicited currents and it dissociates very slowly from the fetal muscle receptor. This toxin causes an apparently irreversible paralysis upon intramuscular injection into gold fish.
產品描述
A Blocker of alpha1/beta1/delta/gamma (fetal muscle) nAChR
產品形式
αA-Conotoxin OIVA (αA-OIVA) is a peptidyl toxin originally isolated from Conus obscures and belongs to the family of short αA-conotoxins (αAS) which includes αA-OIVA, αA-OIVB, αA-PeIVA, and αA-PeIVB. αA-Conotoxin OIVA blocks the fetal muscular subtype nicotinic acetylcholine receptor (α1/β1/γ/δ subunits) (IC50 = 0.51 nM) with 600-fold greater affinity than the adult subtype (IC50 = 310 nM). It completely blocks the elicited currents and it dissociates very slowly from the fetal muscle receptor. This toxin causes an apparently irreversible paralysis upon intramuscular injection into gold fish.
保存建議
艾美捷為您提供的Alonmone Labs原裝進口的AlphaA-Conotoxin OIVA (5 x 50 μg)產品可室溫運輸，建議您在收到產品后將其置于合適的溫度下保存。
