RO 48-8071富馬酸酯產品是Ro 48-8071 is a selective 2,3-Oxidosqualene:lanosterol cyclase (OSC) inhibitor (IC?? = 6.5 nM); blocks cholesterol synthesis in HepG2 cells. ?Ro 48-8071?exerts strong anti-angiogenic activity by impairing endothelial cell adhesion and migration, and by blocking vessel formation in angiogenesis assays.